Welcome to the website designed to display the code and analysis associated with “Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease” (Hook et al., 2018)

This website contains:

  • An About section containing our paper abstract
  • An Analyses section (see navbar above) containing reproducible analysis code
  • A Paper Figures section containing reproducible figure production code
  • A Shiny app that allows for exploration of the expression data
  • A License section containing copyright information

Raw sequencing data can be found at GEO:GSE108020

This website was designed and created by Paul Hook
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Website
email: phook2 [at] jhmi.edu


neuron
A single P7 substantia nigra dopaminergic neuron (60x)
Single molecule FISH against Slc6a3 (green) and Th (red).
The cell nucleus is in blue (DAPI)

Citation

Hook, P.W., McClymont, S.A., Cannon, G.H., Law, W.D., Morton, A.J., Goff, L.A., and McCallion, A.S. (2018). Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease. Am. J. Hum. Genet. 102, 427-446. doi: http://dx.doi.org/10.1016/j.ajhg.2018.02.001

If DOI links do not work yet, find the paper here

Inspiration for this website layout was adapted from:

Last update: 2018-03-01

Code version: 4709191df5af119635644f84988337cbb0157458

This R Markdown site was created with workflowr